Department of

Chemistry & Biochemistry



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Hiroyasu Tachikawa


Jackson State University

Department of Chemistry and Biochemistry

1400 J. R. Lynch Street

P.O. Box 17910

Jackson, MS 39217-0510


Physical location:

John A. Peoples Science Building

Office: room #508



E-mail: hiroyasu.tachikawa@jsums.edu

Tel: (601) 979-3485
Fax: (601) 979-3674



Advanced Analytical Chemistry

Special Topics is Analytical Chemistry

Electrochemical and Optical Sensors


Research Interests:   Electrochemical biosensors.  Raman spectroscopy of thin films and biomolecules

Current research interests of our group are development of biosensors for biomedical import species and characterization of proteins using electrochemical methods and spectroscopies which include Raman, FT-IR, and UV-Vis.


Selected publications

K. Zeng, H. Tachikawa, Z. Zhu, and V. L. Davidson, Amperometric Detection of Histamine   with a Methylamine Dehydrogenase Polypyrrole Based Sensor, Anal, Chem., 72, 2211-2215 (2000).

M. Feng and H. Tachikawa, Raman Spectroscopic and Electrochemical Characterization of  Myoglobin Thin Film: Implication of the Role of Histidine 64 for Fast Heterogeneous Electron Transfer, J. Am. Chem. Soc., 123, 3013-3020 (2001).

L. Bao, D. Sun, H. Tachikawa, and V. L. Davidson, Improved Sensitivity of a Histamine  Sensor Using an Engineered Methylamine Dehydrogenase, Anal. Chem., 74, 1144-1148 (2002).

M. Feng, H. Tachikawa, X. Wang, T.D. Pfister, A.J. Gengenbach, and Y. Lu, Resonance Raman Spectroscopy of Cytochrome c Peroxidase Variants, that Mimic Manganese Peroxidase, J. Biol. Inorg. Chem., 8, 699-706 (2003).

H. Han and H. Tachikawa, Electrochemical Determination of Thiols at Single-Wall Carbon Nanotubes and PQQ Modified Electrodes, Frontier in Bioscience, 10, 931-939 (2005).

A. Ray, M. Feng, and H. Tachikawa, Direct electrochemistry and Raman spectroscopy of sol-gel-encapsulated myoglobin, Langmuir21, 7456-7460 (2005).

X. Li, M. Feng, Y. Wang, H. Tachikawa, and V.L. Davidson, Evidence for redox cooperativity  between c-type hemes of Mau-G which is likely coupled to oxygen activation during tryptopan tryptophyl quinine biosynthesis, Biochemistry45, 821-828 (2006).

Zhang, M. Feng, and H. Tachikawa, Layer-by-layer Fabrication and Direct Electrochemistry of Glucose Oxidase on Single Wall Carbon Nanotubes, Biosens. Bioelectron., 22, 3036-3041 (2007).

M. Feng, H. Han, J. Zhang, and H. Tachikawa, Electrochemical Sensors Based on Carbon Nanotubes in “Electrochemical Sensors, Biosensors and Their Biomedical Application,” X. Zhang, H. Ju, and J. Wang, Eds., Elsevier, 2008, pp 460-494.

M. Feng and H. Tachikawa, Surface-Enhanced Resonance Raman Spectroscopic Characterization of the Protein Native Structure, J. Am. Chem. Soc.,130, 7443-7448 (2008).


Department of Chemistry and Biochemistry, Jackson State University
 1400 J. R. Lynch Street, P.O. Box 17910, Jackson, MS 39217-0510

Tel: 601-979-2171, Fax: 601-979-3674